Pharmacokinetics – 2 compartments versus 3 compartments

Please note that when modelling pharmacokinetic data, 3 compartments is possible. In this case the plasma concentration versus time is fitted with Cp(t) = Ae^(at)+Be^(bt)+Ce^(ct). A 3rd compartment may be indicative of a very slow elimination phase. The highest slope is the distribution phase. The slower phase is the elimination phase. If there are 3 … Continue reading Pharmacokinetics – 2 compartments versus 3 compartments